When you start taking citalopram, a selective serotonin reuptake inhibitor (SSRI) used to treat depression and anxiety. Also known as Celexa, it works by helping your brain maintain healthy serotonin levels. But like all medications, it doesn’t work the same for everyone—and side effects are part of the picture for many people. You’re not alone if you’ve noticed nausea, fatigue, or trouble sleeping in the first few weeks. These aren’t signs you’re doing something wrong. They’re common adjustments your body makes as it gets used to the drug.
Most side effects of citalopram show up early and fade within a couple of weeks. The big ones include dry mouth, drowsiness, sweating, and mild dizziness. Some people feel more anxious at first, which can be scary but usually passes. Less common, but serious, are changes in heart rhythm at higher doses—this is why doctors stick to 40mg max for most adults. If you’re over 60 or have heart issues, your doctor might start you lower. You also need to know that SSRIs like citalopram can cause sexual side effects—lower libido, delayed orgasm, or trouble getting aroused. It’s not talked about enough, but it happens to a lot of people. The good news? These often improve over time, or your doctor can adjust your dose or try a different medication.
What you won’t see in most ads is how antidepressant side effects interact with other meds. Mixing citalopram with painkillers, sleep aids, or even some herbal supplements can raise your risk of serotonin syndrome—a rare but dangerous condition. That’s why it’s critical to tell your doctor everything you’re taking. And if you’ve been on citalopram for months or years, stopping suddenly can cause dizziness, brain zaps, or mood swings. Tapering off slowly under medical care makes all the difference.
Some people never have issues. Others find the side effects too much and switch. Neither outcome means failure. It’s just finding what fits your body. Below, you’ll find real comparisons and experiences from people who’ve walked this path—what worked, what didn’t, and how they managed the tough parts. You’re not guessing anymore. You’ve got clear info ahead.
